Aptamer-Based Origami Paper Analytical Device for Electrochemical Detection of Adenosine

Aptamer-based origami paper analytical device for electrochemical detection of adenosine.

Paper biosensors: an origami sensor is printed on a single piece of paper, folded into a three-dimensional fluidic device, and encapsulated by thermal lamination. Aptamer is trapped in the fluidic channel, where it binds to the target and releases an enzyme to generate a signal. The device is read out using a digital multimeter.

DNA detection using origami paper analytical devices.

We demonstrate the hybridization-induced fluorescence detection of DNA on an origami-based paper analytical device (oPAD). The paper substrate was patterned by wax printing and controlled heating to construct hydrophilic channels and hydrophobic barriers in a three-dimensional fashion. A competitive assay was developed where the analyte, a single-stranded DNA (ssDNA), and a quencher-labeled ssD...

Paper-Based Analytical Device for Quantitative Urinalysis

Paper-based analytical devices are fluidic chips fabricated with extremely inexpensive materials, namely paper, thereby allowing their use as a zero-cost analytical device in third-world countries that lack access to expensive diagnostic infrastructures. The aim of this review is to discuss: (1) microfluidic paper-based analytical devices (µPADs) for quantitative analysis, (2) fabrication of tw...

A Paper-based Analytical Device for Electrochemical Flow Injection Analysis of Glucose in Urine

Paper-based analytical device for electrochemical flow-injection analysis of glucose in urine.

This article describes a new design for a paper-based electrochemical system for flow-injection analysis. Capillary wicking facilitates a gravity-driven flow of buffer solution continuously through paper and nitrocellulose, from a buffer reservoir at one end of the device to a sink at the other. A difference in height between the reservoir and the sink leads to a continuous and constant flow. T...